Broomrape (Orobanche spp) is one of the most dangerous plant parasites in Romania. of weedy of Orobanche cumana Wallr. broomrape populations have been identified in sunflower fields. The parasite is significantly dissemi nated, especially in the south and south-eastern parts of the country. The reac tion of some sunflower cultivars to O. cumana was studied under inoculation and natural contamination conditions. Under the inoculation conditions cre ated at Research Development Institute for Plant Protection in Bucharest, the hybrids HS 1900, Turbo, Justin and Favorit showed absolute resistance. Under natural contamination conditions, at SC Sport Agra srl, Amzacea Dobrogea, best result were showen by Rigasol, Flores, Albani Florena, Sunay, Favorit, Festiv and Turbo. The herbicides Treflan 48 EC and Assert 250 EC were most efficient (>80 %) in controling Orabanche cumana infestation, compared with other herbicides whose efficiency did not exceed 50%.